[20] irio L, Samowitz W, Robertson J , et al. Alleles of APC modulate the frequency and cla es of mutatio that lead to colon poly . Nat Genet ,1998, 20: 385–388.

[21] DiSario J, Kuwada S, Samowitz W, et al. U er gastrointestinal lesio in the attenuated adenomatous polyposis coli syndrome (AAPC). Oral presentation/LCPG-meeting, 2001, Venice, Italy.

[22] Moisio A-L, Järvinen H, Peltomäki P. Genetic and clinical characterization of familial adenomatous polyposis: a population based study. Gut,2002, 50: 845–850.

[23] Davies DR, Armstrong JG, Thakker N , et al. Severe Gardner syndrome in families with mutatio restricted to a ecific region of the APC gene. Am J Hum Genet, 1995, 57: 1151–1158.

[24] Vasen HFA. Clinical diagnosis and management of hereditary colorectal cancer syndromes. J Clin Oncol, 2000, Su l 18 : 81–92.

[25] Friedl W, Ca ari R, Sengteller M ,et al. Can APC mutation analysis contribute to therapeutic decisio in familial adenomatous polyposis? Experience from 680 FAP families. Gut, 2001,48: 515–521.

[26] Bertario L, Ru o A, Sala P, et al. Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis. Int J Cancer, 2001, 95: 102–107.

[27] Hampel H, Peltomaki P. Hereditary colorectal cancer: risk a e ment and management. Clin Genet, 2000, 58: 89-97.

[28] Qualman SJ, Bowen J, Erdman SH. Molecular basis of the brain tumor-polyposis (Turcot) syndrome. Pediatr Dev Pathol, 2003, 6(6):574-576.

[29] De Rosa M, Fasano C, Panariello L, et al. Evidence for a rece ive inheritance of Turcot\'s syndrome caused by compound heterozygous mutatio within the PMS2 gene. Oncogene , 2000, 19(13):1719-1723

[30] Hamilton SR, Liu B, Parso RE, et al. The molecular basis of Turcot’s syndrome. N Engl J Med , 1995, 332:839–847.

[31] To CM, Vasen HF, van Berge Henegouwen G, et al. Genetic evidence that Turcot syndrome is not allelic to familial adenomatous polyposis. Am J Med Genet, 1992 , 43(5):888-893.

[32] Lynch HT, Riley BD, Wei man SM, et al. Hereditary no olyposis colorectal carcinoma (H CC) and H CC-like families: Problems in diagnosis, surveillance, and management. Cancer,2004 ,100(1):53-64.

[33] Cai SJ, Xu Y, Cai GX, et al. Clinical characteristics and diagnosis of patients with hereditary no olyposis colorectal cancer. World J Gastroenterol, 2003, 9(2):284-287.

[34] Lucci-Cordisco E, Zito I, Ge ini F, et al. Hereditary No olyposis Colorectal Cancer and Related Conditio . Am J Med Gene, 2003, 122A:325–334.

[35] Marra G, Boland CR. Hereditary no olyposis colorectal cancer: the syndrome, the genes, and historical per ectives. J Natl Cancer I t, 1995, 87(15):1114-1125.

[36] Tajima A, He MT, Cabrera BL, et al. The mismatch repair complex hMutS alpha recognizes 5-fluorouracil- modified DNA: implicatio for chemose itivity and resistance. Gastroenterology, 2004

上一页  [1] [2] [3] [4] [5] [6] [7] [8] [9] 下一页